Unified framework for growth and division in eukaryotes

Determine whether a unified growth–division framework comparable to bacterial UGD models can be developed and effectively applied to eukaryotic systems (e.g., yeast and mammalian cells), accounting for distinct cell-cycle decision points and differential proteome scaling.

Background

The authors emphasize that bacterial models simplify division control while eukaryotes often regulate at G1/S and show differential proteome scaling.

A unified framework would generalize growth-law concepts, integrating transcriptional and cycle-stage controls in more complex organisms.