Dice Question Streamline Icon: https://streamlinehq.com

How can we measure the extent and pace of changes in the homeodynamic space during ageing?

Develop quantitative methodologies to measure the extent and rate of changes in the homeodynamic space during ageing, enabling assessment of system robustness and adaptability over time.

Information Square Streamline Icon: https://streamlinehq.com

Background

This problem concerns quantifying alterations in homeodynamics—systemic maintenance of stability through change—during ageing.

The authors present it among examples of underrepresented open problems, suggesting methodological gaps and opportunities for innovation.

References

Table 2: Examples of open problems with the least representation in literature, categorised by topic. How can we measure the extent and pace of changes in the homeodynamic space during ageing?

— Open problems in ageing science: A roadmap for biogerontology (2507.18602 - Talay et al., 24 Jul 2025) in Table 2, Results