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Can we apply stem cell therapy based on our own young stem cells (e.g., from cord blood) to modulate ageing?

Assess the feasibility, safety, and efficacy of autologous stem cell therapy using young stem cells (e.g., cord blood) to modulate ageing and improve age-related functional decline.

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Background

Stem cell-based therapies are a major translational avenue in ageing research. This question asks about autologous approaches using younger cells.

The authors identify it among underrepresented open problems, emphasizing the need for rigorous clinical evaluation.

References

Table 2: Examples of open problems with the least representation in literature, categorised by topic. Can we apply stem cell therapy based on our own young stem cells (e.g., from cord blood) to modulate ageing?

Open problems in ageing science: A roadmap for biogerontology (2507.18602 - Talay et al., 24 Jul 2025) in Table 2, Results