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X-ray dark-field via spectral propagation-based imaging (2309.15874v2)

Published 27 Sep 2023 in physics.med-ph, eess.IV, and physics.optics

Abstract: Dark-field X-ray imaging is a novel modality which visualises scattering from unresolved microstructure. Most dark-field imaging techniques rely on crystals or structured illumination, but recent work has shown that dark-field effects are observable in straightforward propagation-based imaging (PBI). Based on the single-material X-ray Fokker--Planck equation with an a priori dark-field energy dependence, we propose an algorithm to extract phase and dark-field effects from dual-energy PBI images. We successfully apply the dark-field retrieval algorithm to simulated and experimental dual-energy data, and show that by accounting for dark-field effects, projected thickness reconstruction is improved compared to the classic Paganin algorithm. With the emergence of spectral detectors, the method could enable single-exposure dark-field imaging of dynamic and living samples.

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References (71)
  1. Spectral Imaging: Dual-Energy, Multi-Energy and Photon-Counting CT. Medical Radiology. Springer International Publishing, Cham, 2022.
  2. Dark-field tomography of an attenuating object using intrinsic x-ray speckle tracking. Journal of Medical Imaging, 9(3):031502, February 2022.
  3. R. E. Alvarez and A. Macovski. Energy-selective reconstructions in X-ray computerised tomography. Physics in Medicine & Biology, 21(5):733, September 1976.
  4. Imaging Breast Microcalcifications Using Dark-Field Signal in Propagation-Based Phase-Contrast Tomography. IEEE Transactions on Medical Imaging, pages 1–1, 2022.
  5. X-ray multimodal imaging using a random-phase object. Physical Review A, 86(6):063813, December 2012.
  6. Two-Dimensional X-Ray Beam Phase Sensing. Physical Review Letters, 108(15):158102, April 2012.
  7. X-ray Dark-Field Radiography: Potential for Visualization of Monosodium Urate Deposition. Investigative Radiology, 55(8):494, August 2020.
  8. Phase objects in synchrotron radiation hard x-ray imaging. Journal of Physics D: Applied Physics, 29(1):133, January 1996.
  9. Directional dark-field retrieval with single-grid x-ray imaging. Optics Express, 31(7):11578–11597, March 2023.
  10. Differential x-ray phase contrast imaging using a shearing interferometer. Applied Physics Letters, 81(17):3287–3289, October 2002.
  11. Tracking based, high-resolution single-shot multimodal x-ray imaging in the laboratory enabled by the sub-pixel resolution capabilities of the MÖNCH detector. Applied Physics Letters, 117(26):264101, December 2020.
  12. Hard X-ray dark-field imaging with incoherent sample illumination. Applied Physics Letters, 104(2):024106, January 2014.
  13. Parametric Image Alignment Using Enhanced Correlation Coefficient Maximization. IEEE Transactions on Pattern Analysis and Machine Intelligence, 30(10):1858–1865, October 2008.
  14. Quantitative In-Line Phase-Contrast Imaging with Multienergy X Rays. Physical Review Letters, 86(25):5827–5830, June 2001.
  15. Dark-field signal extraction in propagation-based phase-contrast imaging. Physics in Medicine & Biology, 65(21):215029, November 2020.
  16. On X-ray phase retrieval from polychromatic images. Optics Communications, 147(4):229–232, February 1998.
  17. Quantifying the x-ray dark-field signal in single-grid imaging. Optics Express, 30(7):10899–10918, March 2022.
  18. Directional x-ray dark-field imaging. Physics in Medicine & Biology, 55(12):3317, May 2010.
  19. 2D-Omnidirectional Hard-X-Ray Scattering Sensitivity in a Single Shot. Physical Review Letters, 116(9):093902, March 2016.
  20. On the origin of speckle in x-ray phase contrast images of lung tissue. Physics in Medicine and Biology, 49(18):4335–4348, September 2004.
  21. CT dose reduction factors in the thousands using X-ray phase contrast. Scientific Reports, 7(1):15953, November 2017.
  22. Emphysema quantified: Mapping regional airway dimensions using 2D phase contrast X-ray imaging. Biomedical Optics Express, 11(8):4176–4190, August 2020.
  23. X-ray phase, absorption and scatter retrieval using two or more phase contrast images. Optics Express, 18(19):19994–20012, September 2010.
  24. X-ray imaging device and associated imaging method, World patent WO/2021/005283, January 2021.
  25. X-ray dark-field and phase retrieval without optics, via the Fokker–Planck equation. IEEE Transactions on Medical Imaging, pages 1–1, 2023.
  26. Lung tumors on multimodal radiographs derived from grating-based X-ray imaging – A feasibility study. Physica Medica, 30(3):352–357, May 2014.
  27. Albert A. Michelson. Studies in Optics. University of Chicago Science Series. The University of Chicago Press, Chicago, Ill., 1927.
  28. Demonstration of X-Ray Talbot Interferometry. Japanese Journal of Applied Physics, 42(7B):L866, July 2003.
  29. Methods for dynamic synchrotron X-ray respiratory imaging in live animals. Journal of Synchrotron Radiation, 27(1):164–175, January 2020.
  30. The projection approximation and edge contrast for x-ray propagation-based phase contrast imaging of a cylindrical edge. Optics Express, 18(10):9865–9878, May 2010.
  31. Applying the Fokker–Planck equation to grating-based x-ray phase and dark-field imaging. Scientific Reports, 9(1):17465, November 2019.
  32. Quantitative single-exposure x-ray phase contrast imaging using a single attenuation grid. Optics Express, 19(20):19781–19789, September 2011.
  33. X-ray phase imaging with a paper analyzer. Applied Physics Letters, 100(12):124102, March 2012.
  34. Alessandro Olivo. Edge-illumination x-ray phase-contrast imaging. Journal of Physics: Condensed Matter, 33(36):363002, July 2021.
  35. Simultaneous phase and amplitude extraction from a single defocused image of a homogeneous object. Journal of Microscopy, 206(1):33–40, 2002.
  36. David Paganin. Coherent X-Ray Optics. Oxford Series on Synchrotron Radiation. Oxford University Press, Oxford, New York, January 2006.
  37. Boosting spatial resolution by incorporating periodic boundary conditions into single-distance hard-x-ray phase retrieval. Journal of Optics, 22(11):115607, October 2020.
  38. Single-image geometric-flow x-ray speckle tracking. Physical Review A, 98(5):053813, November 2018.
  39. X-ray Fokker–Planck equation for paraxial imaging. Scientific Reports, 9(1):17537, November 2019.
  40. Paraxial diffusion-field retrieval. Physical Review A, 108(1):013517, July 2023.
  41. A method to extract quantitative information in analyzer-based x-ray phase contrast imaging. Applied Physics Letters, 82(20):3421–3423, May 2003.
  42. Enhanced detection of threat materials by dark-field x-ray imaging combined with deep neural networks. Nature Communications, 13(1):4651, September 2022.
  43. Single-Shot X-Ray Speckle-Based Imaging of a Single-Material Object. Physical Review Applied, 13(5):054023, May 2020.
  44. X-ray multi-modal intrinsic-speckle-tracking. Journal of Optics, 22(12):125604, November 2020.
  45. Directional dark-field implicit x-ray speckle tracking using an anisotropic-diffusion Fokker-Planck equation. Physical Review A, 104(5):053505, November 2021.
  46. Energy weighted x-ray dark-field imaging. Optics Express, 22(20):24507–24515, October 2014.
  47. Hard-X-ray dark-field imaging using a grating interferometer. Nature Materials, 7(2):134–137, February 2008.
  48. Globally optimal stitching of tiled 3D microscopic image acquisitions. Bioinformatics, 25(11):1463–1465, June 2009.
  49. Implicit tracking approach for X-ray phase-contrast imaging with a random mask and a conventional system. Optica, 8(11):1412–1415, November 2021.
  50. Generalized diffraction enhanced imaging to retrieve absorption, refraction and scattering effects. Journal of Physics D: Applied Physics, 40(10):3077, May 2007.
  51. Material Decomposition Using Spectral Propagation-Based Phase-Contrast X-Ray Imaging. IEEE Transactions on Medical Imaging, 39(12):3891–3899, December 2020.
  52. Spectral propagation-based x-ray phase-contrast computed tomography. Journal of Medical Imaging, 9(3):031506, March 2022.
  53. The xraylib library for X-ray–matter interactions. Recent developments. Spectrochimica Acta Part B: Atomic Spectroscopy, 66(11):776–784, November 2011.
  54. Dual-Energy X-Ray Dark-Field Material Decomposition. IEEE Transactions on Medical Imaging, 40(3):974–985, March 2021.
  55. X-ray directional dark-field imaging using Unified Modulated Pattern Analysis. PLOS ONE, 17(8):e0273315, August 2022.
  56. Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010. JAMA, 307(22):2400–2409, June 2012.
  57. On the possibilities of x-ray phase contrast microimaging by coherent high-energy synchrotron radiation. Review of Scientific Instruments, 66(12):5486–5492, December 1995.
  58. A system for dual-energy radiography. The British Journal of Radiology, 56(667):461–465, July 1983.
  59. Quantitative characterization of the X-ray beam at the Australian Synchrotron Imaging and Medical Beamline (IMBL). Journal of Synchrotron Radiation, 24(1):110–141, January 2017.
  60. Grating-based spectral X-ray dark-field imaging for correlation with structural size measures. Scientific Reports, 10(1):13195, August 2020.
  61. Spectral X-ray dark-field signal characterization from dual-energy projection phase-stepping data with a Talbot-Lau interferometer. Scientific Reports, 13(1):767, January 2023.
  62. Direct Differentiation of Pathological Changes in the Human Lung Parenchyma With Grating-Based Spectral X-ray Dark-Field Radiography. IEEE Transactions on Medical Imaging, 40(6):1568–1578, June 2021.
  63. Michael Reed Teague. Deterministic phase retrieval: A Green’s function solution. Journal of the Optical Society of America, 73(11):1434–1441, November 1983.
  64. Non-invasive classification of microcalcifications with phase-contrast X-ray mammography. Nature Communications, 5(1):3797, May 2014.
  65. Single-shot x-ray differential phase contrast and diffraction imaging using two-dimensional transmission gratings. Optics letters, 35(12):1932–1934, June 2010.
  66. Phase-contrast imaging using polychromatic hard X-rays. Nature, 384(6607):335–338, November 1996.
  67. Dark-field X-ray imaging of unsaturated water transport in porous materials. Applied Physics Letters, 105(15):154105, October 2014.
  68. Improved In vivo Assessment of Pulmonary Fibrosis in Mice using X-Ray Dark-Field Radiography. Scientific Reports, 5(1):17492, December 2015.
  69. Marie-Christine Zdora. State of the Art of X-ray Speckle-Based Phase-Contrast and Dark-Field Imaging. Journal of Imaging, 4(5):60, May 2018.
  70. X-ray Phase-Contrast Imaging and Metrology through Unified Modulated Pattern Analysis. Physical Review Letters, 118(20):203903, May 2017.
  71. Implementation of diffraction-enhanced imaging experiments: At the NSLS and APS. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 450(2):556–567, August 2000.
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