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Can one hear the shape of a population history? (1402.2424v2)

Published 11 Feb 2014 in q-bio.PE, math.ST, and stat.TH

Abstract: Reconstructing past population size from present day genetic data is a major goal of population genetics. Recent empirical studies infer population size history using coalescent-based models applied to a small number of individuals. Here we provide tight bounds on the amount of exact coalescence time data needed to recover the population size history of a single, panmictic population at a certain level of accuracy. In practice, coalescence times are estimated from sequence data and so our lower bounds should be taken as rather conservative.

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