P versus NP strict inclusion
Determine whether the complexity class P is strictly contained in NP, equivalently, establish whether P ≠ NP.
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References
While it is known that P ⊆ NP, whether this inclusion is strict is one of the most important open problems in theoretical computer science.
— On the Complexity of the Secret Protection Problem for Discrete-Event Systems
(2509.14372 - Masopust et al., 17 Sep 2025) in Section 2 (Preliminaries), Subsection "Complexity theory"