General principles governing multiplex topology–dynamics interplay
Establish the general organizing principles that govern the emergence of instabilities, hybrid phase transitions, metastability, and coexistence of dynamical regimes that arise from the interplay between multilayer topology and cross-layer dynamical coupling in multiplex networks, so as to determine when such phenomena occur and how they depend on structural and coupling parameters.
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References
Understanding the general principles that govern these phenomena remains a major open challenge.
— Multilayer network science: theory, methods, and applications
(2511.23371 - Aleta et al., 28 Nov 2025) in Section "Outlook"