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Co-Pilot for Health: Personalized Algorithmic AI Nudging to Improve Health Outcomes (2401.10816v2)

Published 19 Jan 2024 in cs.HC, cs.AI, and cs.LG

Abstract: The ability to shape health behaviors of large populations automatically, across wearable types and disease conditions at scale has tremendous potential to improve global health outcomes. We designed and implemented an AI driven platform for digital algorithmic nudging, enabled by a Graph-Neural Network (GNN) based Recommendation System, and granular health behavior data from wearable fitness devices. Here we describe the efficacy results of this platform with its capabilities of personalized and contextual nudging to $n=84,764$ individuals over a 12-week period in Singapore. We statistically validated that participants in the target group who received such AI optimized daily nudges increased daily physical activity like step count by 6.17% ($p = 3.09\times10{-4}$) and weekly minutes of Moderate to Vigorous Physical Activity (MVPA) by 7.61% ($p = 1.16\times10{-2}$), compared to matched participants in control group who did not receive any nudges. Further, such nudges were very well received, with a 13.1% of nudges sent being opened (open rate), and 11.7% of the opened nudges rated useful compared to 1.9% rated as not useful thereby demonstrating significant improvement in population level engagement metrics.

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References (15)
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[2020] Hoppe, K.K., Thomas, N., Zernick, M., Zella, J.B., Havighurst, T., Kim, K., Williams, M., Niu, B., Lohr, A., Johnson, H.M.: Telehealth with remote blood pressure monitoring compared with standard care for postpartum hypertension. American Journal of Obstetrics & Gynecology 223(4), 585–588 (2020) Milkman et al. [2021] Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Marucci, S., De Iaco, G., Lisco, G., Mariano, F., Giagulli, V.A., Guastamacchia, E., De Pergola, G., Triggiani, V.: Eating disorders and type 1 diabetes: A perspective 22(13), 1245–1251 https://doi.org/10.2174/1871530321666211109152353 Zhu et al. [2021] Zhu, D., Zhao, G., Wang, X.: Association of Smoking and Smoking Cessation With Overall and Cause-Specific Mortality. American Journal of Preventive Medicine 60(4), 504–512 (2021) https://doi.org/10.1016/j.amepre.2020.11.003 Hoppe et al. [2020] Hoppe, K.K., Thomas, N., Zernick, M., Zella, J.B., Havighurst, T., Kim, K., Williams, M., Niu, B., Lohr, A., Johnson, H.M.: Telehealth with remote blood pressure monitoring compared with standard care for postpartum hypertension. American Journal of Obstetrics & Gynecology 223(4), 585–588 (2020) Milkman et al. [2021] Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Zhu, D., Zhao, G., Wang, X.: Association of Smoking and Smoking Cessation With Overall and Cause-Specific Mortality. American Journal of Preventive Medicine 60(4), 504–512 (2021) https://doi.org/10.1016/j.amepre.2020.11.003 Hoppe et al. [2020] Hoppe, K.K., Thomas, N., Zernick, M., Zella, J.B., Havighurst, T., Kim, K., Williams, M., Niu, B., Lohr, A., Johnson, H.M.: Telehealth with remote blood pressure monitoring compared with standard care for postpartum hypertension. American Journal of Obstetrics & Gynecology 223(4), 585–588 (2020) Milkman et al. [2021] Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hoppe, K.K., Thomas, N., Zernick, M., Zella, J.B., Havighurst, T., Kim, K., Williams, M., Niu, B., Lohr, A., Johnson, H.M.: Telehealth with remote blood pressure monitoring compared with standard care for postpartum hypertension. American Journal of Obstetrics & Gynecology 223(4), 585–588 (2020) Milkman et al. [2021] Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. 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[2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. 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[2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. 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[2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. 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[2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Zhu, D., Zhao, G., Wang, X.: Association of Smoking and Smoking Cessation With Overall and Cause-Specific Mortality. American Journal of Preventive Medicine 60(4), 504–512 (2021) https://doi.org/10.1016/j.amepre.2020.11.003 Hoppe et al. [2020] Hoppe, K.K., Thomas, N., Zernick, M., Zella, J.B., Havighurst, T., Kim, K., Williams, M., Niu, B., Lohr, A., Johnson, H.M.: Telehealth with remote blood pressure monitoring compared with standard care for postpartum hypertension. American Journal of Obstetrics & Gynecology 223(4), 585–588 (2020) Milkman et al. [2021] Milkman, K.L., Patel, M.S., Gandhi, L., Graci, H.N., Gromet, D.M., Ho, H., Kay, J.S., Lee, T.W., Akinola, M., Beshears, J., Bogard, J.E., Buttenheim, A., Chabris, C.F., Chapman, G.B., Choi, J.J., Dai, H., Fox, C.R., Goren, A., Hilchey, M.D., Hmurovic, J., John, L.K., Karlan, D., Kim, M., Laibson, D., Lamberton, C., Madrian, B.C., Meyer, M.N., Modanu, M., Nam, J., Rogers, T., Rondina, R., Saccardo, S., Shermohammed, M., Soman, D., Sparks, J., Warren, C., Weber, M., Berman, R., Evans, C.N., Snider, C.K., Tsukayama, E., Bulte, C.V., Volpp, K.G., Duckworth, A.L.: A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proceedings of the National Academy of Sciences 118(20), 2101165118 (2021) https://doi.org/10.1073/pnas.2101165118 https://www.pnas.org/doi/pdf/10.1073/pnas.2101165118 Thaler and Sunstein [2009] Thaler, R.H., Sunstein, C.R.: Nudge: Improving Decisions About Health, Wealth, and Happiness. Penguin Books, ??? (2009) Purohit et al. [2023] Purohit, A., Schöbel, S., Bill, O., Holzer, A.: Nudging to Change, the Role of Digital Health, (2023). https://doi.org/10.1007/978-3-031-17666-1_10 [9] Stepping Up to the Healthy Challenge. Government Technology Agency (2016). https://www.tech.gov.sg/media/technews/stepping-up-to-the-healthy-challenge Accessed 2023-10-19 [10] Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. 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In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. 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[2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. 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JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. 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In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. 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  9. Health Promotion Board Annual Report 2022/2023. Health Promotion Board (2023). https://www.hpb.gov.sg/docs/default-source/pdf/hpb-2022_2023-annual-report.pdf Accessed 2023-10-19 Yao et al. [2022] Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  10. Yao, J., Lim, N., Tan, J., Matthias Müller, A., Dam, R., Chen, C., Tan, C.S., Müller-Riemenschneider, F.: Evaluation of a population-wide mobile health physical activity program in 696 907 adults in singapore. Journal of the American Heart Association 11(12), 022508 (2022) Paluch et al. [2022] Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  11. Paluch, A.E., Bajpai, S., Bassett, D.R., Carnethon, M.R., Ekelund, U., Evenson, K.R., Galuska, D.A., Jefferis, B.J., Kraus, W.E., Lee, I.-M., et al.: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. The Lancet Public Health 7(3), 219–228 (2022) Hupin et al. [2015] Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  12. Hupin, D., Roche, F., Gremeaux, V., Chatard, J.-C., Oriol, M., Gaspoz, J.-M., Barthélémy, J.-C., Edouard, P.: Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥\geq≥ 60 years: a systematic review and meta-analysis. British journal of sports medicine 49(19), 1262–1267 (2015) Watts et al. [2023] Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  13. Watts, E.L., Saint-Maurice, P.F., Doherty, A., Fensom, G.K., Freeman, J.R., Gorzelitz, J.S., Jin, D., McClain, K.M., Papier, K., Patel, S., et al.: Association of accelerometer-measured physical activity level with risks of hospitalization for 25 common health conditions in uk adults. JAMA network open 6(2), 2256186–2256186 (2023) Gilchrist et al. [2020] Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  14. Gilchrist, S.C., Howard, V.J., Akinyemiju, T., Judd, S.E., Cushman, M., Hooker, S.P., Diaz, K.M.: Association of sedentary behavior with cancer mortality in middle-aged and older us adults. JAMA oncology 6(8), 1210–1217 (2020) Wang et al. [2019] Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019) Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)
  15. Wang, X., He, X., Cao, Y., Liu, M., Chua, T.-S.: Kgat: Knowledge graph attention network for recommendation. In: Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining, pp. 950–958 (2019)

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