Universality of infinite exotic smooth structures in dimension four
Determine whether every smoothable topological 4-manifold admits infinitely many pairwise non-diffeomorphic smooth structures, thereby establishing the universality of the phenomenon of infinite exotic smooth structures in dimension four.
References
It is only in dimension four that a topological manifold can carry infinitely many non-diffeomorphic smooth structures. Whether every smoothable topological $4$-manifold has this property is still unknown.
— On smooth structures over $4$-manifolds with fundamental group of even order
(2603.29794 - Ladu et al., 31 Mar 2026) in Introduction (Section 1), first paragraph