Existence of exotic 2-knots (and orientable surfaces) in S^4
Determine whether there exist exotic 2-knots in the 4-sphere S^4, i.e., smoothly embedded 2-spheres in S^4 that are topologically isotopic but not smoothly equivalent; more generally, ascertain whether there exist orientable surfaces in S^4 that are topologically isotopic but smoothly inequivalent.
References
It is unknown whether or not there exist exotic 2-knots (or any orientable surfaces) in $S4$.
— Exotically knotted 2-spheres and the fundamental groups of their complements
(2406.07093 - Benyahia, 11 Jun 2024) in Introduction, paragraph beginning “It is unknown whether or not there exist exotic 2-knots…”.