Dice Question Streamline Icon: https://streamlinehq.com

Turing power of induced HGRNs

Determine whether the subclass of induced hybrid gene regulatory networks, defined for networks with two discrete levels per gene whose celerities are given by c(α)j = ∑_{i: αi=1} ρ(i,j) − ∑_{i: αi=0} ρ(i,j) for a complete weighted directed influence graph H = (V,E,ρ), is Turing-powerful; that is, ascertain whether such induced HGRNs can simulate arbitrary Turing machines via their hybrid trajectories.

Information Square Streamline Icon: https://streamlinehq.com

Background

The paper proves that general hybrid gene regulatory networks (HGRNs) are Turing-powerful by constructing a simulation of a deterministic Turing machine using an HGRN with appropriately designed celerities and multiple discrete levels per gene.

Later, the authors introduce a subclass called induced HGRNs, where each gene has two discrete levels and celerities are linear combinations determined by a complete weighted directed influence graph. The open problem asks whether this restricted, more structured subclass retains Turing power.

References

Further open questions are: 1.) Are induced HGRNs still Turing-powerful?

On Hybrid Gene Regulatory Networks (2404.16197 - Wurm et al., 24 Apr 2024) in Section "Conclusion and Further Questions", Item 1