Existence of pseudo-meridians for all nontrivial knots
Establish whether every nontrivial knot K in S^3 admits a pseudo-meridian, namely an element of the knot group G(K) that normally generates G(K) but is not in the automorphic orbit of any meridian.
References
It is conjectured that every nontrivial knot admits a pseudo-meridian [SWW]. However, this conjecture is widely open.
— Dehn filling and the knot group II: Ubiquity of persistent elements
(2604.01697 - Ito et al., 2 Apr 2026) in Section 6: Persistent elements and pseudo-meridians