Neural state changes across brain regions and state space under coactivation

Determine whether neural state changes associated with muscle coactivation occur across brainstem, cerebellum, visual cortex, somatosensory cortex, and other regions, and identify whether coactivation shifts population neural responses into different parts of state space to modulate responses to sensory feedback.

Background

The paper relates coactivation to potential neural state changes and dynamical systems perspectives of motor cortex, suggesting that coactivation may alter neural trajectories that govern feedback.

It is explicitly unclear whether such state changes are observed across diverse brain regions and whether coactivation shifts population activity to state-space regions that up- or downregulate feedback.

References

It is unclear if these state changes are also evident across various brain regions, such as the brainstem, cerebellum, visual cortex, somatosensory cortex and others, and if changes in muscle coactivation shift the neural population response into different parts of the state space to up- or downregulate responses to sensory feedback [cf. 204].

Muscle coactivation primes the nervous system for fast and task-dependent feedback control (2410.16101 - Maurus et al., 21 Oct 2024) in How does coactivation alter neural responses to sensory feedback?