Intrinsic universality of Tile Automata in dimensions other than two
Determine whether the Tile Automata model is intrinsically universal in one dimension and in three or higher dimensions, specifically whether there exists a finite rule set for Tile Automata that can intrinsically simulate all Tile Automata systems in 1D and in 3D or higher.
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Another obvious open problem is that of dimensions other than two. It is still unknown whether the Tile Automata model is intrinsically universal if you extend the model to one, or to three or higher dimensions.
— Intrinsic Universality in Seeded Active Tile Self-Assembly
(2407.11545 - Gomez et al., 16 Jul 2024) in Section 12, Conclusion