Impact of gap junctions and specific proteins on neural activity

Determine the extent to which gap junctions and the presence of specific proteins influence neural activity dynamics across brain systems to inform data collection priorities and model fidelity requirements for emulation.

Background

The Executive Summary identifies uncertainty about the causal importance of specific structural and molecular features, particularly gap junctions and protein presence, for neural activity.

Resolving this uncertainty would directly guide what structural and molecular measurements are truly necessary for building accurate emulations.