Hilbert–Pólya conjecture
Establish the existence of a self-adjoint operator H such that the eigenvalues of 1/2 + iH coincide with the imaginary parts of the nontrivial zeros of the Riemann zeta function, thereby implying the Riemann hypothesis.
References
According to the Hilbert - Pólya conjecture; if H is a self-adjoint operator and the eigenvalues of 1/2 + iH correspond to the nontrivial zeros of the Riemann zeta function, then the Riemann hypothesis follows.
— Successive generation of nontrivial Riemann zeros from a Wu-Sprung type potential
(2510.16759 - Jaksch, 19 Oct 2025) in Introduction
The Hilbert-Pólya conjecture (1910s) suggests the existence of a self-adjoint operator $H$ such that the non-trivial solutions of $\zeta(1/2 + it) = 0$ are the eigenvalues of $H$.
— The Riemann Hypothesis: Past, Present and a Letter Through Time
(2602.04022 - Connes, 3 Feb 2026) in Subsubsection Hilbert spaces and spectral theory