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Efficacy of chirping harmonic frequencies for enhanced stimulation

Ascertain whether linearly increasing (chirping) harmonic frequencies in the sinusoidal components used for spatio-temporal Fourier synthesis enhance the effectiveness of non-invasive deep-brain stimulation compared to non-chirped harmonics.

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Background

Section 3.2.3 presents an example of chirped stimulation, where the frequencies in the harmonic sum increase linearly over time. This produces time-varying spike patterns distinct from fixed-frequency harmonics.

The authors explicitly identify uncertainty about whether such chirping improves stimulation, highlighting the need for empirical evaluation.

References

In Equation 5 (and Figure 1), the frequencies are linearly growing in time. The resulting time function is interesting and it is an open question if it enhances stimulation or not.

— Non-invasive deep-brain stimulations by spatio-temporal fourier synthesis (2404.02186 - Kish et al., 2 Apr 2024) in Section 3.2.3, page 6