Defining groups (communities/modules) in networks
Determine a precise and operational formal definition of a "group" (also called a community or module) in the mesoscale organization of complex networks, including multilayer networks, that specifies the structural or dynamical criteria a set of nodes must satisfy to constitute a group.
References
However, the definition of what a group exactly corresponds to is an open problem.
A key direction for future research is to determine how network motifs contribute to the emergence of functional communities within biologically plausible neural circuits. In particular, it remains to be established which motifs form the structural and dynamical cores of such communities, and how their spatial and functional organization influences community detectability and structure.
However, efforts to find such modularity have proven difficult, partially because it is not clear in what form we should expect such modularity to appear.