Atiyah–Floer conjecture relating instanton and Lagrangian Floer homologies
Establish the Atiyah–Floer conjecture: given a Heegaard splitting of a closed 3‑manifold Y into handlebodies glued along a surface Σ, prove that the instanton Floer homology of Y is related—precisely, equivalent up to canonical isomorphism—to the Lagrangian Floer homology of a pair of Lagrangian submanifolds in the moduli space of flat connections over Σ associated to the two handlebodies.
References
these are related to Lagrangian Floer theory via the Atiyah-Floer conjecture , which, given a Heegaard splitting of $Y$ as above, relates the instanton Floer homology of $Y$ to the Lagrangian Floer homology of a pair of Lagrangian submanifolds in a moduli space of flat connections over the surface $\Sigma$. See e.g.\ the work of Salamon-Wehrheim and Daemi-Fukaya-Lipyanskiy for progress towards the conjecture.