Global boundedness in a Chemotaxis-May-Nowak model for virus dynamics with logistic damping

Abstract: This paper investigates the following May--Nowak type model for viral infection in a bounded domain $Ω\subset \mathbb{R}<sup>n$, $n \ge 2$: $\begin{cases} u_t = Δu - χ\nabla \cdot (u \nabla v) + κ- u - uw - μ\dfrac{u^{{1+α}}{\ln^k(u+e)},} \[1mm] γv_t = Δv - v + uw, \[1mm] w_t = Δw - w + v, \end{cases}$ where $χ\in \mathbb{R}$, $μ&gt; 0$, $k \in [0,1)$, $α&gt; 0$, and $γ\in {0,1}$. We establish the global existence and uniform-in-time boundedness of classical solutions for suitably regular initial data under one of the following conditions: (A) $γ= 1$, $n = 2$, $k \in [0,1)$, $α= 1$, and $μ&gt; 0$; (B) $γ= 1$, $3 \le n \le 5$, $k = 0$, $α= 1$, and $μ$ is sufficiently large; (C) $γ= 1$, $n \ge 6$, $k = 0$, $α&gt; \frac{n-2}{4}$, and $μ&gt; 0$; (D) $γ= 0$, $n \ge 2$, $k = 0$, $α&gt; \frac{n+2}{2}$, and $μ&gt;0$. In particular, in the physically relevant dimensions $n = 2,3$, both subquadratic and quadratic damping are sufficient to prevent blow-up. Moreover, in the fully parabolic case ($γ= 1$), our results improve upon recent findings by relaxing the condition $α&gt; \frac{n}{2}$ to weaker assumptions within the above parameter regimes.