MultiSense-Pneumo: A Multimodal Learning Framework for Pneumonia Screening in Resource-Constrained Settings

Abstract: Pneumonia remains a leading global cause of morbidity and mortality, particularly in low resource settings where access to imaging, laboratory testing, and specialist care is limited. Clinical assessment relies on heterogeneous evidence, including symptoms, respiratory patterns, and chest imaging, making screening inherently multimodal. However, many existing computational approaches remain unimodal and focus primarily on radiographs. In this work, we present MultiSense-Pneumo, a multimodal framework for pneumonia oriented screening and triage support that integrates structured symptom descriptors, cough audio, spoken language, and chest radiographs. The system combines deterministic symptom triage, LightGBM based acoustic classification, domain adversarial radiograph analysis using ResNet 18, transformer based speech recognition, and an interpretable multimodal fusion operator. Each modality is transformed into a normalized risk signal and aggregated into a unified screening estimate, enabling transparent and modular decision support. MultiSense-Pneumo is designed for real world deployment under modest computational constraints and can operate fully offline on standard laptop class hardware, making it suitable for community health workers, rural clinics, and emergency response settings. Experimental results demonstrate robustness of the radiograph pathway under domain shifts, while highlighting limitations in minority class recall for acoustic signals. MultiSense-Pneumo is intended as a research prototype for screening and triage support rather than a clinically validated diagnostic system.