MIRAGE: Patient-Specific Mixed Reality Coaching for MRI via Depth-Only Markerless Registration and Immersive VR

Abstract: Magnetic resonance imaging (MRI) is an indispensable diagnostic tool, yet the confined bore and acoustic noise can evoke considerable anxiety and claustrophobic reactions. High anxiety leads to motion artifacts, incomplete scans and reliance on pharmacological sedation. MIRAGE (Mixed Reality Anxiety Guidance Environment) harnesses the latest mixed reality (MR) hardware to prepare patients for MRI through immersive virtual reality (VR) and markerless augmented reality (AR) registration. In this paper, we extend our previous work by providing a comprehensive review of related research, detailing the system architecture, and exploring metrics for patient and clinician experience. We also present considerations for clinical deployment of MR systems within hospital workflows. Our results indicate that depth-based registration achieves sub-centimeter accuracy with minimal setup, while the immersive coaching environment reduces patient anxiety and yields favourable usability scores.