AI-VaxGuide: An Agentic RAG-Based LLM for Vaccination Decisions

Abstract: Vaccination plays a vital role in global public health, yet healthcare professionals often struggle to access immunization guidelines quickly and efficiently. National protocols and WHO recommendations are typically extensive and complex, making it difficult to extract precise information, especially during urgent situations. This project tackles that issue by developing a multilingual, intelligent question-answering system that transforms static vaccination guidelines into an interactive and user-friendly knowledge base. Built on a Retrieval-Augmented Generation (RAG) framework and enhanced with agent-based reasoning (Agentic RAG), the system provides accurate, context-sensitive answers to complex medical queries. Evaluation shows that Agentic RAG outperforms traditional methods, particularly in addressing multi-step or ambiguous questions. To support clinical use, the system is integrated into a mobile application designed for real-time, point-of-care access to essential vaccine information. AI-VaxGuide model is publicly available on https://huggingface.co/VaxGuide