RadFlag: A Black-Box Hallucination Detection Method for Medical Vision Language Models

Abstract: Generating accurate radiology reports from medical images is a clinically important but challenging task. While current Vision LLMs (VLMs) show promise, they are prone to generating hallucinations, potentially compromising patient care. We introduce RadFlag, a black-box method to enhance the accuracy of radiology report generation. Our method uses a sampling-based flagging technique to find hallucinatory generations that should be removed. We first sample multiple reports at varying temperatures and then use a LLM to identify claims that are not consistently supported across samples, indicating that the model has low confidence in those claims. Using a calibrated threshold, we flag a fraction of these claims as likely hallucinations, which should undergo extra review or be automatically rejected. Our method achieves high precision when identifying both individual hallucinatory sentences and reports that contain hallucinations. As an easy-to-use, black-box system that only requires access to a model's temperature parameter, RadFlag is compatible with a wide range of radiology report generation models and has the potential to broadly improve the quality of automated radiology reporting.