Enhanced Survival Prediction in Head and Neck Cancer Using Convolutional Block Attention and Multimodal Data Fusion

Abstract: Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in their ability to handle complex multi-modal data. This paper proposes a deep learning-based approach leveraging CT and PET imaging modalities to predict survival outcomes in HNC patients. Our method integrates feature extraction with a Convolutional Block Attention Module (CBAM) and a multi-modal data fusion layer that combines imaging data to generate a compact feature representation. The final prediction is achieved through a fully parametric discrete-time survival model, allowing for flexible hazard functions that overcome the limitations of traditional survival models. We evaluated our approach using the HECKTOR and HEAD-NECK-RADIOMICS- HN1 datasets, demonstrating its superior performance compared to conconventional statistical and machine learning models. The results indicate that our deep learning model significantly improves survival prediction accuracy, offering a robust tool for personalized treatment planning in HNC