Microfluidic front dynamic for the characterization of pumps for long-term autonomous microsystems

Abstract: To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up to one or two hours. We have previously shown that polymeric micropumps combined with plastic microfluidic cartridges constitute a universal self-powered modular microfluidic architecture suitable for moving large volumes of fluids in short times. Herein, we show that polymeric micropumps can provide self-powered flow control for long periods of time in the range of hours and days. The calibration curves of various types of micropumps were obtained including one that maintained the movement of the fluid for 23 hours, advancing the fluid front up to 1.8 meters through a channel with a section of 0.127 mm2. We found that the actuation time of the pump was related to degassing time, the effective surface area and the air recovery rate of the pump. This is the first example of a long operating self-powered microsystem, which may have a great impact in those cases where controlled flow is needed for a long period of time and the use of electronic equipment is not desirable.