Towards Neuromorphic Compression based Neural Sensing for Next-Generation Wireless Implantable Brain Machine Interface

Abstract: This work introduces a neuromorphic compression based neural sensing architecture with address-event representation inspired readout protocol for massively parallel, next-gen wireless iBMI. The architectural trade-offs and implications of the proposed method are quantitatively analyzed in terms of compression ratio and spike information preservation. For the latter, we use metrics such as root-mean-square error and correlation coefficient between the original and recovered signal to assess the effect of neuromorphic compression on spike shape. Furthermore, we use accuracy, sensitivity, and false detection rate to understand the effect of compression on downstream iBMI tasks, specifically, spike detection. We demonstrate that a data compression ratio of $50-100$ can be achieved, $5-18\times$ more than prior work, by selective transmission of event pulses corresponding to neural spikes. A correlation coefficient of $\approx0.9$ and spike detection accuracy of over $90\%$ for the worst-case analysis involving $10K$-channel simulated recording and typical analysis using $100$ or $384$-channel real neural recordings. We also analyze the collision handling capability and scalability of the proposed pipeline.