Abstract: We explore the two-body non-leptonic weak decays of Ωc<sup>0 into final states B<sup>(∗)M and B<sup>(∗)V, where B<sup>(∗) denotes an octet (a decuplet) baryon and M(V) represents a pseudoscalar (vector) meson. We employ the topological SU(3)f approach to depict and parameterize the W-emission and W-exchange processes. We find that the topological parameters can be associated and combined, making them extractable for calculation. Consequently, we explain the partially measured branching fractions relative to B(Ωc<sup>0→</sup>Ω<sup>−π<sup>+), recombined or kept as the following ratios: B(Ωc<sup>0→Ξ<sup>∗0<ˉ/sup></sup>K<sup>∗0)/</sup>B(Ωc<sup>0→Ω<sup>−ρ<sup>+)=0.28±</sup></sup></sup>0.11, B(Ωc<sup>0→Ξ<sup>−π<sup>+)/</sup></sup></sup>B(Ωc<sup>0→Ξ<sup>0<ˉ/sup></sup>K<sup>0)=0.10±</sup>0.02, and B(Ωc<sup>0</sup>→Ω<sup>−</sup>K<sup>+)/</sup>B(Ωc<sup>0</sup>→Ω<sup>−</sup>π<sup>+)=0.06±</sup>0.01. In particular, we present B(Ωc<sup>0</sup>→Ξ<sup>0</sup>π<sup>0)=(2.3±0.2)×</sup>10<sup>−4 as half the value of B(Ωc<sup>0</sup>→Ξ<sup>−</sup>π<sup>+) in the approximate isospin relation, and highlight potential candidates for testing SU(3)f symmetry breaking.