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Hybrid quantum convolutional neural networks model for COVID-19 prediction using chest X-Ray images

Published 8 Feb 2021 in eess.IV, cs.CV, and cs.LG | (2102.06535v1)

Abstract: Despite the great efforts to find an effective way for COVID-19 prediction, the virus nature and mutation represent a critical challenge to diagnose the covered cases. However, developing a model to predict COVID-19 via Chest X-Ray (CXR) images with accurate performance is necessary to help in early diagnosis. In this paper, a hybrid quantum-classical convolutional Neural Networks (HQCNN) model used the random quantum circuits (RQCs) as a base to detect COVID-19 patients with CXR images. A collection of 6952 CXR images, including 1161 COVID-19, 1575 normal, and 5216 pneumonia images, were used as a dataset in this work. The proposed HQCNN model achieved higher performance with an accuracy of 98.4\% and a sensitivity of 99.3\% on the first dataset cases. Besides, it obtained an accuracy of 99\% and a sensitivity of 99.7\% on the second dataset cases. Also, it achieved accuracy, and sensitivity of 88.6\%, and 88.7\%, respectively, on the third multi-class dataset cases. Furthermore, the HQCNN model outperforms various models in balanced accuracy, precision, F1-measure, and AUC-ROC score. The experimental results are achieved by the proposed model prove its ability in predicting positive COVID-19 cases.

Citations (65)

Summary

  • The paper proposes a hybrid quantum-classical CNN model that integrates a quantum convolution layer with traditional CNN layers to enhance COVID-19 detection from chest X-rays.
  • It employs Random Quantum Circuits in the quantum convolution layer for efficient high-dimensional feature extraction, outperforming standard CNN approaches.
  • The model’s impressive sensitivity (up to 99.3%) and high accuracy highlight its potential for early COVID-19 diagnosis and future applications in medical imaging.

Overview of "Hybrid Quantum Convolutional Neural Networks Model for COVID-19 Prediction Using Chest X-Ray Images"

This paper presents an innovative approach to improving COVID-19 detection using a hybrid quantum-classical convolutional neural network (HQCNN) model. By leveraging the capabilities of quantum computing, the proposed model integrates a quantum convolution layer into a classical CNN framework to enhance classification performance on medical image data, specifically chest X-ray (CXR) images.

The authors employ a hybrid quantum-classical structure, where a quantum convolution layer utilizes Random Quantum Circuits (RQCs) for initial feature extraction. This layer's purpose is to exploit the computational advantages offered by quantum systems, such as their ability to operate in high-dimensional spaces and perform complex kernel estimations efficiently. The hybrid model's architecture consists of one quantum convolution layer followed by traditional CNN layers, including standard convolution, max-pooling, and fully connected layers.

The HQCNN model is benchmarked against three datasets comprising 1161 COVID-19, 1575 normal, and 5216 pneumonia CXR images, addressing both binary and multi-class classification tasks. The datasets (D1, D2, and D3) enable the evaluation of the model's ability to distinguish between COVID-19, normal, and pneumonia cases. The hybrid model achieves promising results: 98.4% accuracy and 99.3% sensitivity in the binary dataset differentiating COVID-19 and normal images (D1), 99% accuracy in differentiating COVID-19 and pneumonia images (D2), and 88.6% accuracy in a three-class classification scenario (D3).

The comparison of HQCNN with classic CNNs and various machine learning models, such as MLP, SVM, KNN, AdaBoost, RF, and others, reveals HQCNN's superior precision, particularly in sensitivity and F1-score. The notable results, especially the sensitivity scores of 99.3% (COVID-19/normal) and 99.7% (COVID-19/pneumonia), underscore the model's effectiveness in early COVID-19 detection—a crucial factor in pandemic management and response.

The paper raises interesting questions about the implications of integrating quantum computing techniques into traditionally classical machine learning frameworks. The effective encoding of classical data into quantum states and the subsequent decoding processes remain as challenging aspects that require further exploration to realize the full potential of hybrid models.

In terms of future directions, enhancing the HQCNN by experimenting with different quantum encoding methods, incorporating more quantum layers, and testing on a broader range of clinical datasets could significantly optimize its application. The continuous improvement of quantum hardware and quantum machine learning techniques offers an exciting path for more accurate and efficient medical diagnostics.

The presented HQCNN model marks a substantial contribution to the intersection of quantum computing and artificial intelligence, demonstrating the viability of quantum-enhanced neural networks in complex classification tasks, such as medical image analysis. It paves the way for future research into hybrid quantum-classical algorithms and their applications in other domains requiring high precision, such as genomics, pharmacology, and broader healthcare diagnostics.

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