Regional compartmentalization in multienzyme-related biomaterials system

Abstract: Multienzyme cascaded reactions are widely utilized because they can generate value-added biomaterials and biodevices from simple raw materials. However, how to promote the catalytic efficiency and synergistic effect of the multienzyme system is proved to be a challengeable point. Recent discovery repeatedly emphasized the strategy of assembled multienzyme complexes or forming subcellular compartments for spacial optimization. This highly ordered and tunable organization contributes to various biochemical processes. This dissertation focuses mainly on analysis and progresses in this cascaded strategy, regarding the feasibility of regional compartments for natural or artificial biochemical reactions in vivo and vitro, simultaneously.