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Regulation of interferon production as a potential strategy for COVID-19 treatment
Published 2 Mar 2020 in q-bio.MN and q-bio.SC | (2003.00751v1)
Abstract: Regulating the upstream of the cytokines production could be a promising strategy to the treatment of COVID-19. We suggest to pay more attention to the dysregulated IFN-I production in COVID-19 and to considerate cGAS, ALK and STING as potential therapeutic targets preventing cytokine storm. Approved drugs like suramin and ALK inhibitors are worthy of clinical trials.
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