Inter-slice image augmentation based on frame interpolation for boosting medical image segmentation accuracy

Abstract: We introduce the idea of inter-slice image augmentation whereby the numbers of the medical images and the corresponding segmentation labels are increased between two consecutive images in order to boost medical image segmentation accuracy. Unlike conventional data augmentation methods in medical imaging, which only increase the number of training samples directly by adding new virtual samples using simple parameterized transformations such as rotation, flipping, scaling, etc., we aim to augment data based on the relationship between two consecutive images, which increases not only the number but also the information of training samples. For this purpose, we propose a frame-interpolation-based data augmentation method to generate intermediate medical images and the corresponding segmentation labels between two consecutive images. We train and test a supervised U-Net liver segmentation network on SLIVER07 and CHAOS2019, respectively, with the augmented training samples, and obtain segmentation scores exhibiting significant improvement compared to the conventional augmentation methods.