A simulation-based approach to estimate joint model of longitudinal and event-time data with many missing longitudinal observations

Abstract: Joint models of longitudinal and event-time data have been extensively studied and applied in many different fields. Estimation of joint models is challenging, most present procedures are computational expensive and have a strict requirement on data quality. In this study, a novel simulation-based procedure is proposed to estimate a general family of joint models, which include many widely-applied joint models as special cases. Our procedure can easily handle low-quality data where longitudinal observations are systematically missed for some of the covariate dimensions. In addition, our estimation procedure is compatible with parallel computing framework when combining with stochastic descending algorithm, it is perfectly applicable to massive data and therefore suitable for many financial applications. Consistency and asymptotic normality of our estimator are proved, a simulation study is conducted to illustrate its effectiveness. Finally, as an application, the procedure is applied to estimate pre-payment probability of a massive consumer-loan dataset drawn from one biggest P2P loan platform of China.