Inverse Conditional Probability Weighting with Clustered Data in Causal Inference

Abstract: Estimating the average treatment causal effect in clustered data often involves dealing with unmeasured cluster-specific confounding variables. Such variables may be correlated with the measured unit covariates and outcome. When the correlations are ignored, the causal effect estimation can be biased. By utilizing sufficient statistics, we propose an inverse conditional probability weighting (ICPW) method, which is robust to both (i) the correlation between the unmeasured cluster-specific confounding variable and the covariates and (ii) the correlation between the unmeasured cluster-specific confounding variable and the outcome. Assumptions and conditions for the ICPW method are presented. We establish the asymptotic properties of the proposed estimators. Simulation studies and a case study are presented for illustration.