CNN-Based Automatic Urinary Particles Recognition

Abstract: The urine sediment analysis of particles in microscopic images can assist physicians in evaluating patients with renal and urinary tract diseases. Manual urine sediment examination is labor-intensive, subjective and time-consuming, and the traditional automatic algorithms often extract the hand-crafted features for recognition. Instead of using the hand-crafted features, in this paper, we exploit CNN to learn features in an end-to-end manner to recognize the urine particles. We treat the urine particles recognition as object detection and exploit two state-of-the-art CNN-based object detection methods, Faster R-CNN and SSD, as well as their variants for urine particles recognition. We further investigate different factors involving these CNN-based object detection methods for urine particles recognition. We comprehensively evaluate these methods on a dataset consisting of 5,376 annotated images corresponding to 7 categories of urine particles, i.e., erythrocyte, leukocyte, epithelial cell, crystal, cast, mycete, epithelial nuclei, and obtain a best mAP (mean average precision) of 84.1% while taking only 72 ms per image on a NVIDIA Titan X GPU.