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A self-driven phase transition drives Myxococcus xanthus fruiting body formation (1709.06012v2)
Published 18 Sep 2017 in physics.bio-ph, cond-mat.soft, and q-bio.CB
Abstract: Combining high-resolution single cell tracking experiments with numerical simulations, we show that starvation-induced fruiting body (FB) formation in Myxococcus xanthus is a phase separation driven by cells that tune their motility over time. The phase separation can be understood in terms of cell density and a dimensionless Peclet number that captures cell motility through speed and reversal frequency. Our work suggests that M. xanthus take advantage of a self-driven non-equilibrium phase transition that can be controlled at the single cell level.