Mesoscopic Simulations of Electroosmotic Flow and Electrophoresis in Nanochannels

Abstract: We review recent dissipative particle dynamics (DPD) simulations of electrolyte flow in nanochannels. A method is presented by which the slip length $delta_B$ at the channel boundaries can be tuned systematically from negative to infinity by introducing suitably adjusted wall-fluid friction forces. Using this method, we study electroosmotic flow (EOF) in nanochannels for varying surface slip conditions and fluids of different ionic strength. Analytic expressions for the flow profiles are derived from the Stokes equation, which are in good agreement with the numerical results. Finally, we investigate the influence of EOF on the effective mobility of polyelectrolytes in nanochannels. The relevant quantity characterizing the effect of slippage is found to be the dimensionless quantity $\kappa \delta_B$, where $1/\kappa$ is an effective electrostatic screening length at the channel boundaries.