Parameterize more complex surrogate models for FSI calibration

Develop a practical and identifiable procedure to determine the additional parameters required for more complex surrogate models—such as added lumped-parameter compartments or one-dimensional vessel networks—to replace the fluid-structure interaction component during calibration of coronary boundary conditions in AAOCA simulations.

Background

To enable efficient calibration, the authors replaced the full FSI domain with a simple added RC compartment and acknowledge that richer surrogate representations could be beneficial.

However, they explicitly state that determining the additional parameters for these more complex surrogates is unclear, highlighting a barrier to advancing calibration fidelity while maintaining computational efficiency.