Krivelevich–Sudakov spectral Hamiltonicity conjecture
Determine whether there exists an absolute constant C > 0 such that every d-regular n-vertex (n,d,λ)-graph with spectral ratio d/λ ≥ C is Hamiltonian.
References
Conjecture 1.1. There exists C > 0 such that if d ≥ C then every (n,d,λ)-graph is Hamiltonian. λ
The preceding discussion raises the natural question of whether all $(n,d,\lambda)$-graphs with $\lambda\leq d-2$ are Hamiltonian. The author is not aware of any counterexamples to such a conjecture, despite extensive search with modern AI tools. This should of course be taken with a grain of salt, as it remains very difficult to argue, in general, that a given graph is not Hamiltonian.
A more plausible conjecture is that a wider separation between $d$ and $\lambda$ should be sufficient for Hamiltonicity. For any $\delta\in(0,1)$, there exists $d_0$ so that for every $d\geq d_0$, every $(n,d,\lambda)$-graph with $\lambda\leq (1-\delta)d$ is Hamiltonian.