Perceptual and cognitive consequences of gastric–alpha coupling

Ascertain the perceptual and cognitive consequences of phase-locked modulation of parieto-occipital and right anterior insula alpha amplitude by the gastric rhythm, and determine the pathways by which gastric signals influence cortical oscillations.

Background

Electrogastrogram phase modulates alpha amplitude in parieto-occipital cortex and right anterior insula, suggesting visceral-cortical coupling via vagal and thalamic pathways. The functional significance of this coupling for perception and cognition is unknown.

Establishing behavioral consequences and mechanisms will advance understanding of interoceptive influences on brain rhythms and cognitive function.