Polynomial-time computability of the ELRF distance
Determine whether the ELRF (extended labeled Robinson–Foulds) distance between two labeled trees can be computed in polynomial time by either developing a polynomial-time algorithm or establishing computational hardness for the problem.
References
It is unknown whether this distance can be computed in polynomial time, the main difficulty being that edge operations must have the same label on both endpoints.
— The Path-Label Reconciliation (PLR) Dissimilarity Measure for Gene Trees
(2407.06367 - Sánchez et al., 8 Jul 2024) in Section 1 (Introduction)