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Conjecture 1.4: Cells convert problem signals into formats detectable by other sensors

Show that certain cells transform sensed problem signals into alternative formats that can be detected by other sensors, with the converted signals either being re-detected by the same cell or transmitted to remote cells equipped to respond.

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Background

In multicellular organisms, chemical signaling extends the intracellular problem-propagation principle to intercellular communication. The authors propose that cells re-encode local problems (e.g., via neuropeptides or other molecules) so that more appropriate responder cells can detect and act on them.

This conjecture formalizes the transition from local molecular cascades to distributed problem handling across cell populations, laying groundwork for nervous system evolution.

References

Conjecture 1.4: Some cells can convert a sensed problem into a format detectable by another sensor. Depending on the method, the converted problem signal can then be detected by the same cell, or by one or more remote cells.

A Foundational Theory for Decentralized Sensory Learning (2503.15130 - Mårtensson et al., 19 Mar 2025) in Conjecture 1.4, Section “Multicellular evolution” (Introduction)