Coactivation-induced neural state changes across brain regions

Investigate whether muscle coactivation induces neural population state changes across brainstem, cerebellum, visual cortex, somatosensory cortex, and other regions, and determine whether coactivation shifts neural trajectories to modulate responses to sensory feedback.

Background

Recent work frames motor control in terms of neural trajectories and state-dependent dynamics influenced by task goals, with evidence that specific neurons can excite both agonist and antagonist muscles and that faster movements relate to distinct neural states.

The authors highlight that it is unknown whether coactivation similarly alters neural states across multiple brain regions, and whether such state changes shift population dynamics to up- or downregulate sensory feedback processing.