Estimating Population Burden of Stroke with an Agent-Based Model

Abstract: Stroke is one of the leading causes of death and disability worldwide but it is believed to be highly preventable. The majority of stroke prevention focuses on targeting high-risk individuals but its is important to understand how the targeting of high-risk individuals might impact the overall societal burden of stroke. We propose using an agent-based model that follows agents through their pre-stroke and stroke journey to assess the impacts of different interventions at the population level. We present a case study looking at the impacts of agents being informed of their stroke risk at certain ages and those agents taking measure to reduce their risk. The results of our study show that if agents are aware of their risk and act accordingly we see a significant reduction in strokes and population DALYs. The case study highlights the importance of individuals understanding their own stroke risk for stroke prevention and the usefulness of agent-based models in assessing the impact of stroke interventions.