Lab-on-a-Chip Optical Biosensor Platform: Micro Ring Resonator Integrated with Near-Infrared Fourier Transform Spectrometer

Abstract: A micro-ring-resonator (MRR) optical biosensor based on the evanescent field sensing mechanism has been extensively studied due to its high sensitivity and compact device size. However, a suitable on-chip integrated spectrometer device has to be demonstrated for the lab-on-a-chip applications, which can read the resonance wavelength shift from MRR biosensors based on minuscule changes in refractive index. In this paper, we demonstrated the design and experimental results of the near-infrared lab-on-a-chip optical biosensor platform that monolithically integrates the MRR and the on-chip spectrometer on the silicon-on-insulator (SOI) wafer, which can eliminate the external optical spectrum analyzer for scanning the wavelength spectrum. The symmetric add-drop MRR biosensor is designed to have a free spectral range (FSR) of ~19 nm, and a bulk sensitivity of ~73 nm/RIU; then the drop-port output resonance peaks are reconstructed from the integrated spatial-heterodyne Fourier transform spectrometer (SHFTS) with the spectral resolution of ~3.1 nm and bandwidth of ~50 nm, which results in the limit of detection of 0.042 RIU. The MRR output spectrum with air- and water-claddings are measured and reconstructed from the MRR-SHFTS integrated device experimentally to validate the wavelength shifting measurement.