Quantitative nanoscale MRI with a wide field of view

Abstract: Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable magnetic resonance down on the nanoscale, and sensitivity to single molecules is in sight. Ensemble sensing and wide field imaging improve sensitivity and acquisition speed, but may suffer from inhomogeneous spin control fields, produced by e.g. microstructures in integrated devices, and limited spatial resolution. Here we demonstrate multiplexed nuclear magnetic resonance imaging using diamond nitrogen-vacancy centers in such adverse conditions. We image thin films of calcium fluoride down to $1.2\,\mathrm{nm}$ in thickness with a spatial resolution of $250\,\mathrm{nm}$. This corresponds to a net moment of about 140 nuclear spins within the sensing radius of a given NV in the ensemble.