Novel Meta-Heuristic Model for Discrimination between Iron Deficiency Anemia and B-Thalassemia with CBC Indices Based on Dynamic Harmony Search

Abstract: In recent decades, attention has been directed at anemia classification for various medical purposes, such as thalassemia screening and predicting iron deficiency anemia (IDA). In this study, a new method has been successfully tested for discrimination between IDA and \b{eta}-thalassemia trait (\b{eta}-TT). The method is based on a Dynamic Harmony Search (DHS). Complete blood count (CBC), a fast and inexpensive laboratory test, is used as the input of the system. Other models, such as a genetic programming method called structured representation on genetic algorithm in non-linear function fitting (STROGANOFF), an artificial neural network (ANN), an adaptive neuro-fuzzy inference system (ANFIS), a support vector machine (SVM), k-nearest neighbor (KNN), and certain traditional methods, are compared with the proposed method.