Dice Question Streamline Icon: https://streamlinehq.com

Spatial distribution of exocytosis in tip-growing cells

Determine the spatial distribution of exocytosis along the plasma membrane in tip-growing cells.

Information Square Streamline Icon: https://streamlinehq.com

Background

The spatial pattern of exocytosis is central to models of tip growth, yet direct experimental quantification remains technically challenging. This uncertainty complicates mechanistic understanding of how secretion patterns shape morphologies across species.

The paper presents an inference framework linking cell wall geometry and elastic strains to exocytosis profiles, while acknowledging that direct experimental determination of exocytosis localization remains unresolved due to current measurement limitations.

References

Our findings also shed light on the ongoing debate regarding the spatial distribution of exocytosis in tip-growing cells, which remains unclear due to experimental limitations .

Inferring Exocytosis Profiles from Cell Shapes Using a Dual-Configuration Model of Walled Cell Tip Growth (2506.17472 - Spinelli et al., 20 Jun 2025) in Discussion, Subsection "On the connection between exocytosis and cell shape"