Manifold structure of Busemann G-spaces
Determine whether every Busemann G-space—i.e., a metric space satisfying Busemann’s axioms (finite compactness, existence of geodesic segments with betweenness, local extendability of geodesics, and uniqueness of geodesic extension)—is a topological manifold (locally homeomorphic to Euclidean space).
References
We note that it is not assumed here that the metric space is a manifold. In fact, it is an important open problem, which is presently solved only under some special extra hypotheses, to know whether a G-space is a manifold; see the reviews by Andreev [8] and Berestovskii [11] who made important contributions to this problem.
                — Geometry in the twentieth century: A return to Euclid -- The work of Herbert Busemann
                
                (2406.01109 - Papadopoulos, 3 Jun 2024) in Section 2 (Leibniz, Busemann and a question of Euclidean geometry)