Long-term neurocognitive impact of LLM use
Determine the long-term effects of sustained large language model (LLM) use on human brain function, cognition, and learning outcomes by conducting longitudinal studies, in order to characterize whether LLM use is net positive for human users.
References
We believe that the longitudinal studies are needed in order to understand the long-term impact of the LLMs on the human brain, before LLMs are recognized as something that is net positive for the humans.
— Your Brain on ChatGPT: Accumulation of Cognitive Debt when Using an AI Assistant for Essay Writing Task
(Kosmyna et al., 10 Jun 2025) in Conclusions